Listed in reverse date order:
Praputpittaya 2003 Visual performance in monosodium glutamate-treated rats. Richer 1999 ARMD--pilot (case series) environmental intervention data. Reuters Health Article 1999 Eye disorder linked to ADHD in children. Sadun 1998 Acquired mitochondrial impairment as a cause of optic nerve disease. Feingold 1979 Dietary Management of Nystagmus. Neuman 1978 The danger of "yellow dyes" (tartrazine) to allergic subjects.
- Dietary Management of Nystagmus, B.F. Feingold, Journal of Neural Transmission, 1979, Vol. 45 (2), pp. 107-115.Case reports of response of congenital nystagmus to a diet eliminating synthetic food colors, flavors, BHA, BHT, and salicylates. "...proposal that a variety of neurologic and neuromuscular disturbances ... may be induced by identical chemicals, depending upon the individual's genetic profile and the interaction with other environmental factors."Full text
- The danger of "yellow dyes" (tartrazine) to allergic subjects. Neuman I, Elian R, Nahum H, Shaked P, Creter D. Clin Allergy. 1978 Jan;8(1):65-8." Oral administration of 50 mg tartrazine to 122 patients with a variety of allergic disorders caused the following reactions: general weakness, heatwaves, palpitations, blurred vision, rhinorrhoea, feeling of suffocation, pruritus and urticaria. There was activation of the fibrinolytic pathway . . ."TOP
- Visual performance in monosodium glutamate-treated rats. Praputpittaya C, Wililak A. Nutr Neurosci. 2003 Oct;6(5):301-7." The purpose of this study was to examine the effect of monosodium glutamate on the visual performance in rats. . . . In conclusion, glutamate treatment was shown to cause dose-dependent deficit in visual performance and this may reflect impairment of visual organs and brain function."TOP
See more studies on MSG.
- ARMD--pilot (case series) environmental intervention data., Richer S, Journal of the American Optometric Association 1999 Jan;70(1):24-36"...Fourteen male patients ... were placed on an additional portion of 5 ounces sauted spinach 4 to 7 times per week or lutein-based antioxidant (three patients)... Patients demonstrated short-term positive effects in visual function in one or both eyes with this mild therapeutic approach: Amsler grid (87%); Snellen Acuity (71%); Contrast sensitivity (92%); SKILL (65%); Glare recovery (69%); and Activities of Daily Vision Subscale (60%); ... There was no obvious correlation between ophthalmoscopic appearance of the retina and visual outcome; ... The approach to atrophic ARMD presented here warrants informal practitioner replication and formal randomized prospective clinical case-control evaluation."TOP
- Acquired mitochondrial impairment as a cause of optic nerve disease. Sadun A, Transactions of the American Ophthalmological Society 1998;96:881-923"... Patients from the Cuban epidemic [of blindness] ... did much better once their nutritional status was corrected and exposure to toxins ceased. ... Our animal model duplicated the serologic changes (low folic acid, high formate) as well as these histopathologic changes. ... CONCLUSION: Mitochondria can be impaired either genetically (as in Leber's) or through acquired insults (such as nutritional or toxic factors). Either may challenge energy production in all cells of the body. ..."TOP
Eye disorder linked to ADHD in children
NEW YORK, Apr 14 (Reuters Health) -- An eye disorder appears to be linked to attention-deficit/hyperactivity disorder (ADHD) in children, according to University of California, San Diego researchers.
The eye problem, called convergence insufficiency, is a physical problem of the eye that makes it difficult to keep both eyes focused on a near target. The disorder affects less than 5% of children -- but the research team found that it is three times more common in children with ADHD than in other children.
``This is the first report on the potential connection of these two disorders,'' Dr. David B. Granet said this week during the American Academy of Pediatric Ophthalmology and Strabismus meeting in San Diego.
Granet and colleagues reviewed the records of 266 children identified as having an inability to keep both eyes focused on a close target. The investigators found that 26 children (9.8%) also had a diagnosis of ADHD. ``Twenty of these patients were on medication for ADHD when diagnosed with convergence insufficiency,'' Granet told Reuters Health.
When the researchers reviewed their institution's records of 1,700 children diagnosed with ADHD, they discovered that about 176 also had eye exams, Granet said. ``Of these, almost 16% or 28 children also had convergence insufficiency,'' he added.
This analysis shows that ``children with ADHD had three times the incidence of convergence insufficiency than what was expected in children walking in off the street,'' Granet said.
Convergence insufficiency ``makes it more difficult to concentrate on reading, which is also one of the ways doctors diagnose ADHD,'' Granet commented.
``Convergence insufficiency may not be well known outside the field of eye care specialists,'' Granet told Reuters Health. ``We don't know if children are being misdiagnosed with ADHD when they truly have convergence insufficiency or vice versa,'' he said. ``We also don't know if one causes the other or if medications used for ADHD cause convergence insufficiency,'' he added.
``More study needs to be completed to confirm the connection and to answer these questions,'' Granet said.
Granet also noted that convergence insufficiency responds to eye exercises that can be done at home.